European Commission Research & Innovation Initiatives and Programme Opportunities

Global Health EDCTP3 Joint Undertaking (GH EDCTP3 JU)

Snapshot overview

The Global Health EDCTP3 Joint Undertaking (GH EDCTP3 JU) is a partnership between the European Union (EU) and the EDCTP Association, whose members are several European and African countries. It supports the development of new solutions for reducing the burden of infectious diseases in sub-Saharan Africa, and strengthen research capacities to prepare and respond to re-emerging infectious diseases in this region and worldwide.

Under the 2024 work programme, two calls for proposals are open: a two-stage call covering six topics for Research and Innovation Actions (RIA) and a two-stage call covering one topic for Coordination and Support Actions (CSA).

Name

Global Health EDCTP3 Joint Undertaking (GH EDCTP3 JU)

Institution/ DG/ Agency responsible at EU-level

European Commission’s Directorate-General for Research and Innovation (DG RTD)

Programme

EDCTP3 is a joint undertaking under Horizon Europe covering 2021-2027.

Programme budget

The total indicative budget for the duration of EDCTP3 is EUR 1.6 billion, including EUR 800 million from the EU, EUR 400 million from the EDCTP Association, and EUR 400 million from contributing partners.

Project budget

Depending on the specific project. For further detail, please see below:

  • Accelerating development and integration of therapeutics against Neglected Tropical Diseases (NTDs) in sub-Saharan Africa:
    • Budget: EUR 22 million
    • Contributions: Around EUR 5 million
    • Indicative number of grants: 4
  • Innovative digital health solutions for sub-Saharan Africa:
    • Budget: EUR 22 million
    • Contributions: Around EUR 5 million
    • Indicative number of grants: 4
  • Developing novel, innovative HIV therapeutics for reducing the disease burden of HIV in sub-Saharan Africa:
    • Budget: EUR 22 million
    • Contributions: Around EUR 5 million
    • Indicative number of grants: 4
  • Tackling Antimicrobial Resistance (AMR) through R&D in novel and existing antimicrobials (2024): EUR 24 million:
    • Budget: EUR 24 million
    • Contributions: Around EUR 6 million
    • Indicative number of grants: 4
  • Global Health EDCTP3 JU training fellowship with return phase:
    • Budget: EUR 3,5 million
    • Contributions: Around EUR 3,5 million
    • Indicative number of grants: 1
  • Research on existing Malaria vaccines and development of new promising candidates:
    • Budget: EUR 30 million
    • Contributions: Around EUR 15 million
    • Indicative number of grants: 2
  • New tools, technologies and approaches for vector control in sub-Saharan Africa:
    • Budget: EUR 18,432,000
    • Contributions: Around EUR 6,140,000
    • Indicative number of grants: 3
Type of funding

Grants (contribution may be required depending on the specific call)

Target participants
  • SMEs
  • Large enterprises
  • NPOs
  • Academia
  • Individuals
  • Public sector
Programme scope

Infectious diseases, such as HIV, malaria and Tuberculosis, but also other poverty related and neglected infectious diseases, with a focus on Africa, especially in sub-Saharan Africa. Covers emerging infectious diseases threats, antimicrobial resistance and non-communicable diseases and co-morbidities.

Participant criteria

Funding from the Global Health EDCTP3 Joint Undertaking is allocated to entities eligible for funding under the Horizon Europe programme and established in the constituent states of the EDCTP Association.

Project duration

Depending on the specific project

Average time from submission to project kick-off

The indicative timeline for evaluation and grant agreement, described in Annex F of the Horizon Europe Work Programme 2023-2024, is as follows:

  • Information on the outcome of the evaluation: Around 5 months from the deadline for submission
  • Indicative date for the signing of grant agreements: Around 8 months from the deadline for submission

For two-stage calls, the timing is different (for the evaluation result: around 3 months from the deadline for submission for the first stage and around 5 months from the deadline for submission for the second stage; for signature of the grant agreement: around 8 months from the second stage deadline for submission).

R&D stage

Early-stage research and development

Intellectual property

Unknown

Project database
  • Accelerating development and integration of therapeutics against Neglected Tropical Diseases (NTDs) in sub-Saharan Africa
      • Call for proposals here
  • Innovative digital health solutions for sub-Saharan Africa
      • Call for proposals here
  • Developing novel, innovative HIV therapeutics for reducing the disease burden of HIV in sub-Saharan Africa
      • Call for proposals here
  • Tackling Antimicrobial Resistance (AMR) through R&D in novel and existing antimicrobials
      • Call for proposals here
  • Global Health EDCTP3 JU training fellowship with return phase
      • Call for proposals here
  • Research on existing Malaria vaccines and development of new promising candidates
      • Call for proposals here
  • New tools, technologies and approaches for vector control in sub-Saharan Africa
      • Call for proposals here
Status
  • Accelerating development and integration of therapeutics against Neglected Tropical Diseases (NTDs) in sub-Saharan Africa: Open
      • Publication of the call: 18 January 2024
      • Submission deadline: First stage 4 April 2024, Second stage 17 September 2024
  • Innovative digital health solutions for sub-Saharan Africa: Open
      • Publication of the call: 18 January 2024
      • Submission deadline: First stage 4 April 2024, Second stage 17 September 2024
  • Developing novel, innovative HIV therapeutics for reducing the disease burden of HIV in sub-Saharan Africa: Open
      • Publication of the call: 18 January 2024
      • Submission deadline: First stage 4 April 2024, Second stage 17 September 2024
  • Tackling Antimicrobial Resistance (AMR) through R&D in novel and existing antimicrobials: Open
      • Publication of the call: 18 January 2024
      • Submission deadline: First stage 4 April 2024, Second stage 17 September 2024
  • Global Health EDCTP3 JU training fellowship with return phase: Open
      • Publication of the call: 18 January 2024
      • Submission deadline: First stage 4 April 2024, Second stage 17 September 2024
  • Research on existing Malaria vaccines and development of new promising candidates: Open
      • Publication of the call: 18 January 2024
      • Submission deadline: First stage 4 April 2024, Second stage 17 September 2024
  • New tools, technologies and approaches for vector control in sub-Saharan Africa: Open
      • Publication of the call: 18 January 2024
      • Submission deadline: First stage 4 April 2024, Second stage 17 September 2024

What type of funding are you looking for?

  • Grant:
    Grants are direct financial contributions from the European Union budget awarded by way of a donation to third-party beneficiaries (usually non-profit-making organisations) engaged in activities that serve EU policies.
  • Loan:
    Loans are measures of financial support provided on a complementary basis from the budget in order to address specific policy objectives of the European Union. Such instruments are implemented in partnership with public and private institutions such as banks, venture capitalists or angel investors.

What stage of development are you seeking R&I funding for?

  • Basic science: Basic science covers the various exploratory steps even prior to discovery
  • Discovery: Drug discovery aims to find potential disease-altering targets, such as a gene or a protein in humans. Prior to testing candidate compounds for safety
  • Preclinical development: Preclinical development concerns the testing of candidate compounds for safety in specific indications or disease conditions. Introduction of candidate compound in living biological systems (animals)
  • Phase 1 clinical trials: These are the first clinical trials on humans(usually 20-80 volunteers) testing the safety, side effects, best dose, and timing of a new treatment
  • Phase 21/2b clinical trials: This is the follow-up trial with roughly 100 to 500 patients to analyse efficacy and safety
  • Phase 3 clinical trials: These trials usually involve several hundreds to many thousands patients and tests the results of earlier clinical trials on larger populations to generate robust data on safety, efficacy and benefit-risk relationships of the medicine. Comparison to placebo and/or active comparator (best standard treatment)
  • Registration & launch: This concerns post-study, prior to launch, activities related to market launch. That can include, among others, marketing authorisation, regulatory activities, post-study communication or HTA
  • Introduction & delivery: This concerns all post-launch activities

What do you want to develop?

  • Treatment or vaccine:
    Refers to a drug or vaccine
  • Diagnostic or medical device:
    Refers to diagnostics and medical devices
  • Platform:
    Refers to a digital health platform or medical app
  • Knowledge:
    Refers to conducting research to help build our understanding on a topic
  • Standards:
    Refers to creating a benchmark for a specific issue

What type of organisation are you?

  • Small & medium-sized enterprises:
    <250 employees, annual revenue <EUR 50,000,000) or balance sheet < EUR43 million. This applies to individual firms only. If part of larger group, check the User Guide: https://ec.europa.eu/docsroom/documents/42921
  • Large enterprises:
    >250 employees or annual revenue > EUR 50,000,000. Non-profit organisation (non-governmental organisations that are recognised with a non-profit status)
  • Non-profit organisations:
    Non-governmental organisations that are recognised with a non-profit status
  • Academic:
    Linked to a university or equivalent
  • Public:
    Local, regional, federal government representative

What stage of diagnostics development does your research aim to cover?

  • Development:
    Product development
  • Validation:
    Lab and clinical validation
  • Evaluation & Authorisation:
    Regulatory approvals
  • Access:
    Monitoring

What stage of medicine or vaccine development does your research aim to cover?

  • Discovery and development:
    Identification of promising compounds for development and initial experiments to gather information
  • Preclinical research:
    Laboratory and animal testing to answer basic questions about safety
  • Phase 0 (clinical):
    Testing on limited number of subjects at subtherapeutic doses
  • Phase I (clinical):
    Testing on <100 healthy subjects with the disease/condition
  • Phase II (clinical):
    Testing on up to several hundred subjects with the disease/condition
  • Phase III (clinical):
    Testing on 300 to 3,000 volunteers with the disease/condition
  • Preregistration / Phase IV (clinical):
    Testing on several thousand volunteers with the disease/condition
  • Clinical (unspecified):
    Clinical phase unknown
  • Evaluation & Authorisation:
    Activities relating to marketing authorisation
  • Access:
    Monitoring

Where are you based?

  • Africa : Algeria, Angola, Benin, Botswana, Burkina Faso, Burundi, Cabo Verde, Cameroon, Central African Republic (CAR), Chad, Comoros, Congo (Democratic Republic of the), Congo (Republic of the), Cote d’Ivoire, Djibouti, Egypt, Equatorial Guinea, Eritrea, Eswatini, Ethiopia, Gabon, Gambia, Ghana, Guinea, Guinea-Bissau, Kenya, Lesotho, Liberia, Libya, Madagascar, Malawi, Mali, Mauritania, Mauritius, Morocco, Mozambique, Namibia, Niger, Nigeria, Rwanda, Sao Tome and Principe, Senegal, Seychelles, Sierra Leone, Somalia, South Africa, South Sudan, Sudan, Tanzania, Togo, Tunisia, Uganda, Zambia, Zimbabwe
  • America (non-US & Canada) : Antigua and Barbuda, Argentina, Bahamas, Barbados, Belize, Bolivia, Brazil, Chile, Colombia, Costa Rica, Cuba, Dominica, Dominican Republic, Ecuador, El Salvador, Grenada, Guatemala, Guyana, Haiti, Honduras, Jamaica, Mexico, Nicaragua, Panama, Paraguay, Peru, Saint Kitts and Nevis, Saint Lucia, Saint Vincent and the Grenadines, Suriname, Trinidad and Tobago, Uruguay, Venezuela
  • Asia-Pacific : Afghanistan, Australia, Bangladesh, Bhutan, Burma, Brunei, Cambodia, China (including special administrative regions of Hong Kong and Macau), Cook Islands, Federated States of Micronesia, Fiji, India, Indonesia, Japan, Kiribati, Laos, Malaysia, Maldives, Marshall Islands, Mongolia, Nepal, New Caledonia, New Zealand, Niue, North Korea, Pakistan, Palau, Papua New Guinea, Philippines, Singapore, Solomon Islands, South Korea, Sri Lanka, Taiwan, Thailand, Timor-Leste, Tonga, Tuvalu, Vanuatu, Vietnam
  • Europe (non-EU) : Albania, Andorra, Armenia, Azerbaijan, Belarus, Bosnia and Herzegovina, Georgia, Iceland, Kosovo, Liechtenstein, Moldova, Monaco, Montenegro, North Macedonia, Norway, Russia, San Marino, Serbia, Switzerland, Turkey, Ukraine, United Kingdom
  • European Union (EU) : Austria, Belgium, Bulgaria, Croatia, Republic of Cyprus, Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Latvia, Lithuania, Luxembourg, Malta, Netherlands, Poland, Portugal, Romania, Slovakia, Slovenia, Spain, Sweden
  • Middle East : Cyprus, Lebanon, Syria, Iraq, Iran, Israel, Jordan, Saudi Arabia, Kuwait, Qatar, Bahrain, United Arab Emirates, Oman, Yemen
  • United States (US) & Canada : United States, Canada

What type of organisation are you?

  • Small and medium-sized enterprise (SME):
    Staff headcount 50 < and turnover ≤ EUR 10 m or balance sheet total ≤ EUR 10 m (small); Staff headcount 250 < and turnover ≤ EUR 50 m or balance sheet total ≤ EUR 43 m (medium)
  • Large enterprise:
    Staff headcount > 250
  • Non-profit organisation:
    Association, foundation, or equivalent
  • Academic:
    University, research institute, or equivalent
  • Individual:
    Private citizen
  • Public sector:
    Local, regional, federal government representative
  • Other:
    None of the above or uncertain